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Given that our findings suggest that generic pricing may be cost-effective, payers could explore adjusting reimbursement criteria, notes lead investigator Abhinav Sharma, MD, PhD, DREAM-CV Lab, Research Institute, and Centre for Outcome Research & Evaluation, McGill University Health Centre

A dose-response analysis from the same research suggested that 2,000 mg per day provides the maximum weight loss effect in adults, with a non-linear relationship meaning that taking more than 2,000 mg does not produce proportionally greater benefits

While it is too early to draw definitive conclusions, GLP-1s represent a meaningful area of innovation at the intersection of neurobiology, metabolism, and addiction medicine

These compounds bridge the gap between simplistic herbal formulations and structurally fragile peptides

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